The Albumin-Coated Knitted Dacron Aortic Prosthesis: A Clinical Study

      This paper is only available as a PDF. To read, Please Download here.
      Between June 1987 and January 1989, a total of 123 albumin-coated, knitted Dacron aortic prosthetic grafts were used in 120 patients. The aim of this study was to determine the degree of graft impermeability to blood as well as short - and medium-term patency of the graft material. Patients were grouped as follows: group I (64 patients), operation for chronic aortoiliac obliteration; group II (45 patients), operation for abdominal aortic aneurysm; group III (14 patients), operation on the thoracic aorta. Ninety-one bifurcated and 32 albumin-coated grafts were inserted. Abnormal bleeding was seen in five cases but did not lead to any adverse clinical consequences and stopped spontaneously. In group I there were two instances of early thromboses thought to be due to hemodynamic compromise, which were successfully treated surgically. In group III, two patients had early thrombosis due to coagulation disorders. These were treated by thrombectomy and medical therapy. One hundred and fourteen patients (95%) were followed for a mean of 8.2 months (range 1–18 months). Three late complications related to the prosthesis were observed: one patient had a false aneurysm occurring at month 14 and was corrected surgically. Two other patients experienced thrombosis of their graft treated by extraanatomical bypasses. Primary patency at the end of the follow-up period was 93% while secondary patency was 98%. There were no early or late infectious complications. We conclude that albumin-coated Dacron prosthesis is a reliable material for aortic replacement. Intraoperative loss of blood is reduced and short-and medium-term patency is comparable to those of uncoated aortic prosthetic material.

      Key Words

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Annals of Vascular Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Cavallaro A
        • Sciacca V
        • Gallo P
        • et al.
        Pretreatment of dacron prostheses with gelatin: experimental research and clinical evaluation.
        J Vasc Surg. 1989; 17: 83-89
        • Harris PL
        Comparison between a new collagen impregnated graft (Microvel®) in the management of aortic bifurcation disease.
        Angio Archiv. 1985; 9: 67-72
        • Guidoin R
        • Snyder R
        • Martin L
        • et al.
        Albumin-coating of a knitted polyester arterial prosthesis: an alternative to preclotting.
        Ann Thorac Surg. 1984; 37: 458-465
        • Guidoin R
        • Riao TJ
        • Torche D
        • et al.
        An albumin-coated polyester arterial prosthesis made ready to anastomose: in vivo evaluation in dogs.
        Clin Mat. 1988; 3: 119-131
        • Guidoin R
        • Marceau D
        • Merhi Y
        • et al.
        An albumin-coated polyester arterial prosthesis made ready to anastomose: in vitro evaluation.
        Clin Mat. 1988; 3: 195-207
        • Norgren L
        • Berggren U
        • Parsson H
        • et al.
        How does Hemashield® affect surgical technique? Clinical results in aortic reconstruction.
        Angio Archiv. 1985; 9: 39-41
        • Branchereau A
        • Ondo N'Dong LA
        • Selve L.
        Antibioprophylaxie en chirurgie artérielle restauratrice.
        Presse Med. 1987; 16: 1633-1635
        • Rutherford R
        • Flanigan P
        • Wittemore A
        • et al.
        Suggested standards for reports dealing with lower extremity ischemia.
        J Vasc Surg. 1986; 4: 80-94
        • Guidoin R
        • King M
        • Gosselin C
        • et al.
        Les prothèses artérielles en polyester.
        RMB. 1982; 4: 13-25
        • Sigot-Luizard MF
        • Sigot M
        • Dormurado D
        • et al.
        Evaluation de la biocompatibilité des matériaux utilisés en prothèse interne.
        RMB. 1981; 3: 179-186
        • Davidson J
        • Beucrart D
        • Edwards WH
        • et al.
        The role of graft material in aortic reconstructive surgery.
        Ann Surg. 1983; 197: 714-720
        • Darling RC
        • Brewster DC
        • Hallett JW
        Aortoiliac reconstruction.
        Surg Clin North Am. 1979; 59: 565-579
        • Bunt TJ
        Synthetic vascular graft infection: I. Graft infections.
        Surgery. 1983; 93: 733-746