Malignant Fibrous Histiocytoma Arising From Descending Thoracic Aorta

      This paper is only available as a PDF. To read, Please Download here.
      Cases of malignant fibrous histiocytoma arising from the aorta are rare and have a dismal outlook despite treatment. The longest reported survival period following resection is only 28 months. A patient with malignant fibrous histiocytoma of the descending thoracic aorta was successfully treated with resection and reconstruction with a prosthetic graft. The patient developed metastatic disease eight months postoperatively. With aggressive triple regimen chemotherapy, complete remission has been obtained. The patient is alive and free of disease six years postoperatively.

      Key Words

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Annals of Vascular Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Salm R
        Primary fibrosarcoma of aorta.
        Cancer. 1972; 29: 73
        • O'Brien JE
        • Stout AP
        Malignant fibrous xanthomas.
        Cancer. 1964; 17: 1145-1148
        • Weiss SW
        • Enzinger FM
        Malignant fibrous histiocytoma: an analysis of 200 cases.
        Cancer. 1978; 41: 2250-2255
        • Kaplan BJ
        • Day AL
        Cervical carotid artery dissection secondary to malignant fibrous histiocytoma.
        Neurosurgery. 1987; 21: 571-574
        • Hoseman W
        • Schepke P
        Malignant fibrous histiocytoma as pulsating neck tumor—diagnosis using intraarterial digital subtraction angiography.
        HNO (Nurnberg). 1985; 33: 380-382
        • Carlin BW
        • Moser KM
        Pulmonary artery obstruction due to malignant fibrous histiocytoma.
        Chest. 1987; 92: 173-175
        • Misra DP
        • Sunderrajan EV
        • Rosenholtz MJ
        • Hurst DJ
        Malignant fibrous histiocytoma in the lung masquerading as recurrent pulmonary thromboembolism.
        Cancer. 1983; 51: 538-541
        • Van Damme H
        • Vandeerdeweg W
        • Schoofs E
        Malignant fibrous histiocytoma of the pulmonary artery.
        Ann Surg. 1987; 205: 203-207
        • Kern SE
        • Cowen ME
        • Abrams GD
        Malignant fibrous histiocytoma of the heart presenting as unilateral pulmonary thromboembolism and infarct.
        Hum Pathol. 1985; 16: 1279-1281
        • Parussis E
        Primares malignes fibroses polymorphes histiozytom der aorta.
        Pathologe. 1985; 6: 282-285
        • Hermanek P
        • Gentsch HH
        • Scheele J
        Maligne tumoren der groBen GefaBe.
        Chirurg. 1985; 56: 120-122
        • Hermanek P
        • Lang M
        • Raithel D
        Primares malignes fibroses histiozytoma der aorta.
        Deutsch Med Wochenschr. 1983; 42: 1616-1617
        • Guvendik L
        • Ross JK
        • Marshall RJ
        Primary aortic malignant fibrous histiocytoma: a successfully treated case by surgical excision.
        Ann Thorac Surg. 1986; 42: 578-580
        • Wenker JC
        • Becker GJ
        • Reilly MK
        • Tejada E
        • Cockerill EM
        Malignant myxoid emboli in a patient with a primary tumor of the aorta.
        Virch Invest Radiol. 1986; 21: 928-931
        • Weinberg DS
        • Maini BS
        Primary sarcoma of the aorta associated with a vascular prosthesis. A case report.
        Cancer. 1980; 46: 398-399
        • Chen KTK
        Primary malignant fibrous histiocytoma of the aorta.
        Cancer. 1981; 48: 840-844
        • Crum CP
        • Feldman PS
        • Nolan SP
        Primary fibroxanthosarcoma of the thoracic aorta.
        Virch Arch Pathol Anat. 1978; 1: 379-381
        • Crawford ES
        Diseases of the Aorta. Williams & Wilkins, Baltimore1984: 387-394
        • Devita JT
        • Hellman S
        • Rosenberg SA
        Cancer Principles and Practice of Oncology. J.B. Lippincott Company, Philadelphia1985: 1244-1291