Abstract
Background
Vaccine Induced Thrombotic Thrombocytopenia (VITT) is a rare complication following
ChAdOx1 (AstraZeneca) vaccination. Venous thrombosis in unusual sites such as splachnic
or intracranial thrombosis, is the commonest manifestation.
Case report
We report a 35-year-old male patient who presented with acute left leg ischemia and
thrombocytopenia 11-days after vaccination requiring emergent thrombectomy. During
work-up, a localized thrombus was detected in the left carotid bifurcation mandating
carotid thrombectomy. Localized right iliac thrombus causing a non-limiting flow stenosis
was treated conservatively. The platelet aggregating capacity of patient's plasma
was confirmed in a functional assay, thereby establishing VITT.
Conclusion
To the best of our knowledge this is the first case presenting multiple arterial thromboses
requiring surgical treatment after ChAdOx1 vaccination.
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Article info
Publication history
Published online: October 10, 2021
Accepted:
July 8,
2021
Received:
June 22,
2021
Footnotes
Conflicts of interest: The authors declare no Conflicts of interest.
Identification
Copyright
© 2021 Elsevier Inc. All rights reserved.
