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Role of Platelet to Lymphocyte Ratio and Red Cell Distribution Width in Predicting Postoperative Complications in Patients with Acute Mesenteric Ischemia

  • Shou-Liang Miao
    Affiliations
    Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
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  • Ting-Ting Lin
    Affiliations
    Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
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  • Lang Chen
    Affiliations
    The First Clinical Medical Institute of Wenzhou Medical University, Wenzhou, Zhejiang, China
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  • Author Footnotes
    ∗ These two authors participated equally to this work and should share “corresponding authorship”.
    Xiang-Wu Zheng
    Correspondence
    Correspondence to: Xiang-Wu Zheng, MD, Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Ouhai District, Wenzhou, Zhejiang, 325015, People's Republic of China.
    Footnotes
    ∗ These two authors participated equally to this work and should share “corresponding authorship”.
    Affiliations
    Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
    Search for articles by this author
  • Author Footnotes
    ∗ These two authors participated equally to this work and should share “corresponding authorship”.
    Fan-Feng Chen
    Correspondence
    Correspondence to: Fan-Feng Chen, MD, Department of Vascular Surgery, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Ouhai District, Wenzhou, Zhejiang, 325015, People's Republic of China.
    Footnotes
    ∗ These two authors participated equally to this work and should share “corresponding authorship”.
    Affiliations
    Department of Vascular Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
    Search for articles by this author
  • Author Footnotes
    ∗ These two authors participated equally to this work and should share “corresponding authorship”.
Published:March 02, 2022DOI:https://doi.org/10.1016/j.avsg.2022.01.036

      Background

      The predictive values of the platelet to lymphocyte ratio (PLR) and red cell distribution width (RDW) have been demonstrated in different types of abdominal surgery. The aim of this study was to investigate the interest of the preoperative PLR and RDW as predictors of 30-day postoperative complications in patients with acute mesenteric ischemia (AMI).

      Methods

      Clinical data of 105 AMI patients were retrospectively reviewed. Postoperative complications were evaluated by the Clavien–Dindo classification. The cutoff values for neutrophil to lymphocyte ratio (NLR), PLR, and RDW were determined by receiver operating characteristic curves. Univariate and multivariate analyses evaluating the risk factors for postoperative complications were performed.

      Results

      In the univariate analyses, advanced age, female, anemia, high white blood cell (WBC), high PLR, high NLR, high RDW, Charlson comorbidity index (CCI) score ≥2, and bowel resection were associated with the postoperative complications. A multivariable analysis revealed that advanced age, high PLR, high RDW, and bowel resection were independent predictors of postoperative complications.

      Conclusions

      The PLR and RDW might play important roles in evaluation of the risk of postoperative complications in AMI patients. The preoperative PLR and RDW are simple and useful predictors of postoperative complications in AMI patients.
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