Background
Diet is fundamental to maintaining and improving human health. There is ample evidence
identifying the beneficial and/or harmful effects of diet on noncommunicable diseases
such as obesity, diabetes mellitus, and cardiovascular disease. However, the associations
of the diet to chronic venous disease has not been fully described.
Methods
Data were collected through a cross-sectional survey conducted on 1,571 community-dwelling
adults in 2018. Diet intake frequency was assessed using valid food group consumption
frequency questionnaires. Multivariable logistic regression models were used to evaluate
the association of diet with chronic venous disease.
Results
In total, 857 participants were diagnosed with chronic venous disease. Those who ate
soybean products daily and 4–6 days/week had a 51–31% lower risk of chronic venous
disease compared with those who only occasionally consumed soybean food, respectively.
Participants who consumed eggs and egg products 1–3 days/week versus those who only
occasionally ate eggs showed a lower risk of chronic venous disease [odds ratio (OR)
0.542, 95% confidence interval (CI) 0.375–0.782]. Eating fried food 4–6 days each
week was associated with an increased risk of chronic venous disease (OR 3.872, 95%
CI 1.263–11.599) compared with those who only occasionally ate fried foods. There
is a decreasing tendency of the adjusted OR for eating soybean products daily with
the severity of disease [chronic venous disease (C0–C2): OR 0.575, 95% CI 0.408–0.812;
chronic venous insufficiency (C3–C6): OR 0.222, 95% CI 0.114–0.435].
Conclusions
A higher frequency in the consumption of soybean products and eggs were associated
with a lower risk of chronic venous disease. High level of fried food consumption
was positively associated with risk of chronic venous disease. There are certain specific
trends in relation to dietary consumption and severity of disease, although these
trends were less strong. These associations are largely independent of other dietary
and nondietary factors.
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References
- Venous symptoms: the sym vein consensus statement developed under the auspices of the European venous forum.Int Angiol. 2016; 35: 374-398
- Management of chronic venous disorders of the lower limbs. Guidelines according to scientific evidence. Part I.Int Angiol. 2018; 37: 181-254
- An epidemiological survey of venous disease among general practitioner attendees in different geographical regions on the globe: the final results of the vein Consult Program.Angiology. 2018; 69: 779-785
- The epidemiology of chronic venous insufficiency and varicose veins.Ann Epidemiol. 2005; 15: 175-184
- Epidemiology of chronic venous disease.Phlebology. 2008; 23: 103-111
- Editor's choice - management of chronic venous disease: clinical practice guidelines of the European Society for Vascular Surgery (ESVS).Eur J Vasc Endovasc Surg. 2015; 49: 678-737
- Nutrition for the prevention of chronic diseases.Med Clin North Am. 2016; 100: 1185-1198
- Global diets link Environmental sustainability and human health.Nature. 2014; 515: 518-522
- Varicose veins, nature's error or man's? Some implications of the darwinian theory.Lancet. 1959; 2: 172-175
- Fiber intake, constipation, and risk of varicose veins in the general population: Edinburgh vein study.J Clin Epidemiol. 2001; 54: 423-429
- Lifestyle factors and varicose veins: does cross-sectional design result in underestimate of the risk?.Phlebology. 2010; 25: 201-206
- Cohort profile: the Kadoorie study of chronic disease in China (KSCDC).Int J Epidemiol. 2005; 34: 1243-1249
- Revision of the ceap classification for chronic venous disorders: consensus statement.J Vasc Surg. 2004; 40: 1248-1252
- Clinical, aetiological, anatomical and pathological classification (ceap): gold standard and limits.Phlebology. 2012; 27: 114-118
- Varicose veins, cotton workers, and diet.Br Med J. 1969; 3: 55-56
- An epidemiological study of varicose veins in Indian railroad workers from the south and north of India, with special reference to the causation and prevention of varicose veins.Int J Epidemiol. 1972; 1: 177-183
- [Western diet: risk factors for varices and explanation of their different frequencies among French people and immigrants].Phlebologie. 1981; 34: 235-243
- Soy consumption, adhesion molecules, and pro-inflammatory cytokines: a brief review of the literature.Nutr Rev. 2009; 67: 213-221
- Non-isoflavone phytochemicals in soy and their health effects.J Agric Food Chem. 2010; 58: 8119-8133
- Nutritional quality of legumes, and their role in cardiometabolic risk prevention: a review.J Med Food. 2013; 16: 185-198
- Egg consumption improves vascular and gut microbiota function without increasing inflammatory, metabolic, and oxidative stress markers.Food Sci Nutr. 2022; 10: 295-304
- Fried food consumption and cardiovascular health: a review of current evidence.Nutrients. 2015; 7: 8424-8430
Article Info
Publication History
Published online: July 08, 2022
Accepted:
June 19,
2022
Received:
March 10,
2022
Publication stage
In Press Journal Pre-ProofFootnotes
Sources of funding: This work was supported by the Key Research and Development (R&D) Projects of Shanxi Province (No. 201803D31147 ).
Declarations of interest: None.
Author contributions: Bin Hao and Tao Yang researched literature and conceived the study. Jing He and Fan Ma was involved in protocol development, gaining ethical approval and data analysis. Jing He and Fan Ma wrote the first draft of the manuscript. Jie Yao and Shyamal Premaratne drafted the article or revised it critically for important intellectual content. As members of the investigation team, Hongxia Gao and others participated in the whole process of epidemiological investigation. All authors reviewed and edited the manuscript and approved the final version of the manuscript.
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