Background
The aim of this study was to explore the predictive value of endoleak in short-term
follow-up after endovascular aortic repair (EVAR) of abdominal aortic aneurysm (AAA)
via perioperative laboratory indicators.
Methods
A retrospective study included 200 consecutive patients who received standard EVAR
treatment for AAA and were followed-up for 1 year. Binary logistic regression analysis
was used to evaluate the correlation of the level and changes of perioperative laboratory
indicators with the endoleak events during the follow-up. The receiver operating characteristic
(ROC) curve was used to assess the predictive value of laboratory indicators for endoleak.
Results
A total of 45 cases of endoleak events occurred during follow-up. Binary logistic
regression analysis showed that postoperative fibrinogen decrease, perioperative lymphocyte
difference and lymphocyte monocyte ratio (LMR) difference were independent risk factors
for short term endoleak. The area under the ROC curve (AUC) of postoperative fibrinogen
was 0.596, the cut-off value was 284 mg/dl, and the corresponding specificity and
sensitivity were 0.644 and 0.568. The AUC of the lymphocyte difference was 0.622,
the cut-off value was −0.45 × 109/L, and the corresponding specificity and sensitivity were 0.651 and 0.568. The AUC
of the LMR difference was 0.597, the cut-off value was −1.719, and the corresponding
specificity and sensitivity were 0.631 and 0.614.
Conclusions
Decrease of postoperative fibrinogen, increase of lymphocyte difference and LMR difference
were independent predictive factors for endoleak in short-term follow-up after EVAR
for AAA.
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Article info
Publication history
Published online: January 12, 2023
Accepted:
November 24,
2022
Received:
September 4,
2022
Footnotes
The first two authors contribute to this work equally.
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.
