Background
The introduction of endovascular aortic arch repair (EAR) represents a paradigm shift
in the management of complex arch pathologies usually treated with open surgical repair
(OSR). This shift in treatment of aortic arch disease has also been accompanied with
a rise in commercial interest in EAR resulting in the development of several endografts.
However, the RELAY™ Branched by Terumo Aortic can be considered the prime endograft
choice. In this international original study, a retrospective comparative analysis
of international prospective outcomes data on the single- and double-branch RELAY
stent grafts is provided.
Methods
International data on EAR procedures carried out from January 2019 to January 2022
using the single- and double-branch RELAY endograft configurations were collected
prospectively. Follow-up data were collected at 30 days, 6 months, 12 months, and
24 months postoperatively. Retrospective descriptive analysis, logistic regression,
and Kaplan-Meier analysis were performed.
Results
A total of 125 patients were included, out of which 17 (13.6%) received the single-branch
RELAY and 108 the double-branch device. In the single-branch group, no mortalities,
strokes, or reinterventions were recoded over 24 months of follow-up. The rates of
these outcomes were higher in the other group; however, the differences did not reach
significance. Target vessel patency was maintained at 100% throughout the study period
with the single-branched RELAY. Overall, our Kaplan-Meier analyses proved that both
configurations of RELAY Branched yield excellent short- and mid-term survival and
freedom from reintervention.
Conclusions
Our series has clearly demonstrated that EAR using RELAY Branched is a highly efficacious
strategy that yields very favorable results which can be considered superior to other
EAR devices as well as OSR. Nevertheless, it seems that clinical outcomes with the
single-branch RELAY are more optimal than with the double-branch device.
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Article info
Publication history
Published online: February 22, 2023
Accepted:
February 10,
2023
Received:
January 7,
2023
Publication stage
In Press Journal Pre-ProofFootnotes
Conflict of interest: None.
Funding sources: None.
Author contributions: Authors MJ, AOS, MT, RC, and LA were involved in the literature search and manuscript writing. MJ and AOS performed the statistical analysis and provided the tables and figures. GP reviewed the manuscript and provided feedback. All authors contributed to the manuscript and approved its final submitted version.
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